Interpretation of Vitamin D Plus Test:

Common causes of hypocalcemia (decreased value of calcium) are chronic renal failure, hypomagnesemia and hypoalbuminemia. Common causes of hypercalcemia (increased value of calcium) are increased intestinal absorption (Vitamin D intoxication), increased skeletal reabsorption (immobilization), or a combination of mechanisms (primary hyperparathyroidism). Primary hyperparathyroidism and malignancy accounts for 90-95% of all cases of hypercalcemia.

Elevated levels of phosphate are an indication of kidney disease while low levels indicate hyperparathyroidism, malnutrition and alcoholism.

Quantification of circulating intact PTH assists in the differential diagnosis hypoparathyroidism, hyperparathyroidism, hypercalcemia or malignancy. Interpretation of intact PTH values should always take into account serum Calcium results and inter-relationship between these two elements in various disorders involving PTH & Calcium. It is recommended that the intact PTH results should always be interpreted with caution & with consideration of the overall manifestations even when used in conjunction with calcium values.